Would you take this drug?

Here’s a little quiz for you.

Step 1: Read the following warning label for a prescription drug (I’ve substituted “[REDACTED]” for the name of the drug).

Some people have had changes in behavior, hostility, agitation, depressed mood, suicidal thoughts or actions while using [REDACTED]. Some people had these symptoms when they began taking [REDACTED], and others developed them after several weeks of treatment or after stopping [REDACTED].

If you, your family, or caregiver notice agitation, hostility, depression, or changes in behavior, thinking, or mood that are not typical for you, or you develop suicidal thoughts or actions, anxiety, panic, aggression, anger, mania, abnormal sensations, hallucinations, paranoia, or confusion, stop taking [REDACTED] and call your doctor right away.

Also tell your doctor about any history of depression or other mental health problems before taking [REDACTED], as these symptoms may worsen while taking [REDACTED].

Do not take [REDACTED] if you have had a serious allergic or skin reaction to [REDACTED]. Some people can have serious skin reactions while taking [REDACTED], some of which can become life-threatening. These can include rash, swelling, redness, and peeling of the skin.

Some people can have allergic reactions to [REDACTED], some of which can be life-threatening and include: swelling of the face, mouth, and throat that can cause trouble breathing. If you have these symptoms or have a rash with peeling skin or blisters in your mouth, stop taking [REDACTED] and get medical attention right away.

Tell your doctor if you have a history of heart or blood vessel problems before starting [REDACTED], or if you have a history of these problems and have any new or worse symptoms during treatment with [REDACTED]. Get emergency medical help right away if you have any symptoms of a heart attack.

In clinical trials, the most common side effects of [REDACTED] include: Nausea (30%), Sleep problems (trouble sleeping, changes in dreaming), Constipation, Gas, Vomiting. If you have side effects that bother you or don’t go away, tell your doctor. You may have trouble sleeping, vivid, unusual or strange dreams while taking [REDACTED].

Step 2: Before reading further, answer this question: How seriously ill would you have to be before you would be willing to take this drug as a possible treatment? Terminally ill with cancer? A mild cold? Or somewhere in between?

Okay. The drug name is now revealed: It’s Chantix and it’s purpose is to help you stop smoking.

You read correctly. A drug whose sole benefit is to possibly get you to stop smoking can lead to suicide, a fatal skin reaction or a heart attack. Among other unpleasant side effects. Granted, smoking is a serious problem with its own life-threatening possibility. But I have to wonder about taking a drug that, at least in the short term, seems potentially worse than the problem it’s trying to fix.

It’s not just Chantix. Whenever I see a drug advertised on TV, there’s at least a 50:50 chance that the list of possible problems is enough to scare me from ever wanting to take the drug. Some of these drugs may be worth the risk. But you wouldn’t know it from the ridiculous television ads. And yet…these ads must work or I wouldn’t keep seeing them. I guess people attend more to the happy people on the screen than to what the announcer is saying may be about to happen to them.

Play the Lottery? Don’t Bet On It

Time magazine has some financial advice for you. The only problem is, if you follow their advice, you are nearly 100% certain to lose money. Maybe it’s just me, but I don’t think this is the sort of advice Time (or anyone) should be doling out.

Specifically, an article by Bill Saporito asks and answers: Play the Lottery? You Bet. You read correctly. The column argues that buying lottery tickets on a regular basis, something that even Time magazine itself (in a previous article) asserted you should never do, is actually money well spent.

This has to be one of the most inane and potentially harmful columns ever to appear in Time. The author should be embarrassed by the column. Time should be ashamed for publishing it.

By what torturous and irrational reasoning did Mr. Saporito come to this fallacious conclusion? Let’s take a closer look.

What are the odds?

The author admits that the odds of one ticket winning the Powerball Lottery are incredibly low — as in 1 in 195,249,054. In his attempt to convey just how low these odds are, Saporito warns: “You have a better chance of being struck by lightning.”

True. But not nearly true enough. If you buy one lottery ticket a week for a year, the odds that you will win the lottery are 1 in 195,249,054/52 which works out to 1 in 3,754,790. In contrast, the National Weather Service reports that the odds of being struck by lightning in a given year is 1 in 1,000,000. In other words, the odds that you will win the lottery are more close to the odds of being struck by lightning 4 times in one year!

The odds go up or down depending on how many lottery tickets you buy in a year. If you only buy one ticket a year, you would have to get struck by lightning 195 times during that year to match the lottery winning odds. On the other hand, if you buy 4 tickets a week for a year (as Mr. Saporito does), the odds of winning are indeed close to the odds of being struck by lightning. Of course, even this is not anything that should get your hopes up.

Let’s look at this one other way. Suppose you buy one ticket a week in a lottery where your odds of winning are 52 to 1. This would mean that you could expect to win the lottery on an average of once a year. With the Powerball’s odds of 195,249,054 to 1, you could expect to win on average once every 3.75 million years! In other words, the odds of winning the Powerball are close to the odds of winning if you never play at all. They are both about zero.

And yet, $58.8 billion dollars was spent on state-supported lotteries last year.

A regressive tax?

Mr. Saporito points out a second criticism against lotteries: They amount to a regressive tax. That is, the lower your annual income, the greater percentage of that income is used up when you buy lottery tickets. Buying $1000 worth of lottery tickets a year is 5% of your income if you make $20,000 a year. But it is only 0.5% of your income if you earn $200,000 a year. Given that those in the lower income brackets tend to buy lottery tickets with greater frequency than those in the upper brackets, this is a double whammy: lottery ticket purchases most hurt those that can least afford it. Indeed, a study cited by Saporito showed lotteries eating up as much a 3.1% of income that would otherwise go to food, rent and clothing.

How does this make sense?

At this point, you might expect Saporito to strongly advocate against lottery ticket purchases. That’s certainly what the data he presents would suggest. But no, he instead recommends the opposite. Huh? How can this be? Mr. Saporito attempts three answers:

First, Mr. Saporito advocates for the entertainment value of the lottery. The enjoyment you get imagining what you would do if you won makes it worth buying a ticket. In some sense, it’s the same enjoyment you might get from playing a slot machine in Las Vegas and hoping for the jackpot. I concede this point — up to a point. It only makes sense if you truly enjoy the process (to me, buying a lottery ticket and waiting to see if I won is no fun at all), you don’t buy more tickets than you can afford (which may be close to zero for low income individuals), and you truly understand how badly the odds are stacked against you. I would suggest that very few people meet these combined criteria.

Saporito’s second argument boils down to this quote: “And there are many other even more foolish places to waste money (than the lottery). Why does Wall Street keep coming to mind?” By this, Mr. Saporito appears to be implying you are better off playing the lottery than investing your money in stock.

Here is where Saporito’s logic truly comes off the rails. As cited in the article, if you had invested money in the stock market for the past ten years (which happen to be among the worst ten years in the history of the stock market), you would have lost 1.54% of your investment. In other words, a $1000 investment would now be worth a bit over $984. Had you invested the same money in the lottery, you would almost certainly have $0 left. By what screwy reasoning does this make the lottery a better deal than the stock market? Never mind that throughout most of the last 60 years, you would have actually made money in the stock market during any ten year period.

Anyway, it’s not as if the stock market is the only alternative place for your lottery money. If you just put the money in a bank, even at the current low interest rates, you’d be better off. Heck, if you spent it on a flat-panel television, you’d probably have more enjoyment than from lottery tickets.

Finally, Mr. Saporito concludes: “So I’ll continue to buy my $4 worth of lotto tickets each week.” This is the final bit of illogic. If all you want is to enjoy an “imaginary jackpot”, why spend $4 a week? Couldn’t you get the same enjoyment from $1 a week, and save the extra $3? If not, if spending more money somehow increases your enjoyment, where does this progression stop? What makes $4 the stopping point? Why not $40 or $400 dollars a week? Saporito offers no advice here.

Take my advice instead. Ignore Mr. Saporito. Stay away from the lottery. Unless the near certainty of losing money appeals to you.

Steve Jobs

This is not a recounting of all that Steve Jobs has accomplished, the ways in which he has forever altered the trajectory of our world. You can find plenty of such tributes on the web.

Today, I merely want to say thank you to Steve Jobs for the huge and enduring impact he has had on my own life.

The first computer I bought was a original Macintosh back in 1984. I never looked back. Every single computer I have owned since then has been from Apple — all the way to my current sheer delight, a MacBook Air.

I did make one brief detour back in the 1990′s and purchased a Gateway PC. It was not a replacement for my Mac, but an addition. I had agreed to write a cross-platform book and needed the Gateway to do the PC side of the book. I hated every minute of it. I sold the computer within a year and withdrew from my book contract.

In this century, my love affair with Apple products extended beyond computers to iPods and iPhones and iPads. [The Macworld Expo where Steve introduced the iPhone is still the most amazing fall-off-my-chair event I have ever attended.] Again, I never considered buying any competing device. It was Apple or nothing.

For me, like for so many others, Apple products were unlike any other purchase. I didn’t simply buy an Apple computer, I established a relationship with it. It became a member of our family. I recognized a spark in the design of Apple products that was missing from the competition, no matter how things might have stacked up on a spec sheet.

My passion for Apple products eventually blossomed into a satisfying and enriching career writing about Apple. It began with writing magazine articles and eventually extended to books and websites.

I bled six-colors, as they used to say back when the Apple logo sported a rainbow.

I say all this because I am certain that, without Steve Jobs at Apple’s helm, none of this would have happened. The products that I so admire would never have been created without Steve to oversee their development. Whatever else might have filled their place would have been far less exciting. They would never have ignited the passion that led to my career as a technology writer. The arc of the past four decades of my life has been altered by Steve Jobs more than any other person outside of my immediate family. For this, I will be forever grateful.

I didn’t agree with everything Steve did. In recent years, I have been especially critical of Steve’s positions regarding control of the App Store and jailbreaking of iOS devices. Regardless, with Steve in charge, I remained confident that the big decisions would be in the best interest of Apple and its customers. Put it this way: I’d much rather have a CEO that created an iPhone that disallows jailbreaking, than someone who would have never created the iPhone in the first place.

I am one of the lucky ones. I have been able to live the advice Steve Jobs gave at his 2005 Stanford commencement address:

“You’ve got to find what you love. And that is as true for your work as it is for your lovers. Your work is going to fill a large part of your life, and the only way to be truly satisfied is to do what you believe is great work. And the only way to do great work is to love what you do. If you haven’t found it yet, keep looking. Don’t settle. As with all matters of the heart, you’ll know when you find it.”

I found it, Steve. Thanks to you.

Steve Jobs died today. There are no words that can express the sorrow I am now feeling. The world was a better place because Steve Jobs was in it. Life goes on — as it always does. But the world will never seem quite the same again.

Intelligence, Evolution and Politics

In the most recent Sunday New York Times, Frank Bruni argues that being “smart”, at least in the scholarly academic intellectual sense that President Obama is generally considered to be smart, is not a guarantee that a President will be a strong leader, or always make wise policy decisions, or have the ability to effectively carry out their decisions.

I agree with the basic assertion. There are multiple components to intelligence. Being good at one aspect does not automatically make you superior in all aspects. If it were otherwise, it would mean that nearly everyone on the faculty at Harvard would necessarily make a great president. I don’t think anyone believes that. It’s no different than athletic prowess. Being a good sprinter does not mean you are also a good long distance runner.

However, it does not follow that “intellectual” intelligence is irrelevant to being a good President. I believe a substantially above average intellectual intelligence should be a bar which all viable presidential candidates should be expected to surmount. In the extremes, there is no argument here. That is, while I doubt anyone would contend that being able to read guarantees that a person will be a great President, we all expect our President to be able to read.

So where do we set the bar? How much intellectual skill should be required for a Presidential candidate?

Here is where we can get into legitimate debate. If we can all agree that being “smart” is a desirable attribute, I hope we can similarly agree that being “dumb” should be case for elimination from consideration. [“Dumb” is a hard word to define here (and has an insulting context). But I’m not sure what other word better fits here as the opposite of “smart.”]

One way to demonstrate that you are not “dumb” is to show you are not ignorant of and do not reject basic tenets of science. We wouldn’t want a president making decisions about global policy if he thought the world was flat. We wouldn’t want a president in charge of the space program who though the sun revolved around the earth. We wouldn’t want a president in charge of the economy who planned to spend huge sums of money on finding a way to turn lead into gold. We wouldn’t want a president overseeing our national health care policy who rejected the idea that bacteria is a major cause of disease.

In this same list of basic tenets is evolution. As Dobzhansky famously stated: “Nothing in Biology Makes Sense Except in the Light of Evolution.” To biologists (and virtually all other reputable scientists), support for “creationism” or “intelligent design” has no valid basis. It makes no more sense than supporting the notion that the earth is flat or asserting that gravity is a questionable concept. We should certainly not be teaching it in science classes in schools. Just because an idea exists, and some people believe it, is not a sufficient reason to include the idea in a science curriculum.

[Note: I’ve written several prior columns here on the evolution “controversy.” This is not the place for me to do another. If you’re interested in this matter, I would recommend Jerry A. Coyne’s Why Evolution is True. I would also direct you to the 2005 Kitzmiller vs. Dover Area School District decision, in which a Republican-appointed judge gave a definitive ruling rejecting intelligent design as a thinly veiled attempt to get creationism back in schools, that creationism was religion and not science, and that as such creationism in schools should be rejected. Finally, I strongly recommend you check out “Understanding Evolution: 17 Misconceptions and Their Responses.”]

This gets me, finally, to the subject of politics — and especially to the current crop of Republicans seeking their party’s nomination for President. As covered in a recent article in the San Francisco Chronicle, the candidates’ positions on this issue, while not exactly surprising, are appalling.
Every one of them, except for John Huntsman, gave at least minimal support to a belief in creationism and in teaching “intelligent design” in schools. Here are three examples:

• Rick Perry has described himself as “a firm believer in intelligent design as a matter of faith and intellect.”

• Ron Paul said he does not accept the theory of evolution.

• Rick Santorum calls himself a “fierce believer” in creationism.

There are only two explanations for such “dumb” statements. The first is that the candidates are being hypocritical, that they don’t really believe what they are saying. Rather, they are saying it only because they fear that saying anything else will so antagonize the conservative base of their party (most of whom cling to the “creationism” fantasy) that they lose any chance to get the nomination.

The second is that they truly believe what they are saying.

In either case, it should be sufficient to eliminate such candidates from consideration. In the first case, not only are they liars, but they are deliberately misleading to their own supporters. In the second case, they have shown they are unable to surmount the intelligence bar that I argued should be a minimum requirement for the job.

I don’t expect the candidates or the Republican party in general, to follow my recommendations. I just ask that you keep all this in mind when you go to the polls.